The SCRS Site Invoiceables Toolkit helps sites spot missed billable activities and improve budgeting and invoicing. Use the calculators and resources below to estimate invoiceables and understand the true cost of running a trial.

Study start-up is resource-intensive, requiring sites to complete dozens of tasks before screening begins. When underfunded or overlooked, these steps cause delays and enrollment bottlenecks. Sponsors and CROs who understand this work are better able to support timely activation and strong study performance.

Reimbursement and stipends ease the financial burden on participants and help make trials more equitable. Sponsors and CROs need to understand how these payments work and why standardizing them matters for retention and diversity. When support is predictable, transparent, and timely, participants stay engaged and sites run more smoothly.

Successful trial recruitment means investing in people, systems, and outreach that reflect the communities sites serve. With sites reporting $5k–$25k+ in recruitment costs, it is vital to understand the real costs behind recruitment.

This resource breaks down the five core questions every site’s KPIs should answer, covering quality, financial, start-up, enrollment, and scale metrics. It includes a 7-metric CRO scorecard example, common blind spots in how CROs evaluate sites, and a framework for tracking profitability and capacity.